Consumer AI Top 100: Miami's OpenEvidence Debuts at 47

a16z's seventh Top 100 finds consumer AI usage is wide but shallow, with spending concentrated at the top. Miami's OpenEvidence debuts on the web list at No. 47.

a16z’s seventh Top 100 Gen AI Consumer Apps finds consumer AI is wide but not deep. Only 4.5% of US consumers pay for a top chatbot. Miami’s OpenEvidence debuts on the web list at No. 47. #ConsumerAI #a16z #OpenEvidence #MiamiTech

Consumer AI is wide but not deep, according to the seventh edition of a16z’s Top 100 Gen AI Consumer Apps.

Nearly half of US consumers now report using AI, a16z writes. Only 25% use it daily.

What Does the Report Say About Paying for Consumer AI?

As of August, 4.5% of eligible US consumers had an active paid personal subscription to ChatGPT, Gemini or Claude, a16z reports. A year earlier it was 2.1%.

Spending is concentrated. The top 1% of payers account for 19.5% of observed consumer AI spend, more than the bottom 50% combined.

That top 1% pays an average of $903 per month. The median payer spends $25, according to the report.

The top 10% of spenders account for roughly half of all observed spending. They disproportionately buy coding, productivity and creative tools.

Few payers branch out. Only 13% of users who pay for one AI product pay for even one other, a16z reports.

For the first time, the list adds a ranking by observed spending. The data comes from YipitData and covers US consumer cards only.

a16z cautions that it is drawn from panels, not a census. It should not be read as total company revenue.

Where Does OpenEvidence Land on the List?

OpenEvidence enters the web list at No. 47. a16z cites it as an example of a startup that owns an audience with specific needs, in this case physicians.

The report estimates that 50% to 60% of US physicians use OpenEvidence. It says the company also now partially monetizes through ads.

Becker’s Hospital Review also says more than half of US physicians are regular users. A 2025 survey by career platform Offcall found nearly three times as many physicians use OpenEvidence as ChatGPT.

MAIN reported that Miami’s OpenEvidence reached a $15 billion valuation. The company moved its headquarters to Miami in 2025.

MAIN’s detailed overview of OpenEvidence covers its evidence base, ad model and open questions.

One disclosure matters here. a16z and Byers Capital led OpenEvidence’s $250 million round at a $15 billion valuation, Becker’s Hospital Review reported. a16z is not a neutral observer.

Only seven products make the web, mobile and spending lists. They include ChatGPT, Claude, Suno, Perplexity, Photoroom, Canva and Notion. OpenEvidence is not among them.

The ranking still shows something useful. A tool built for one professional audience can earn a place beside general-purpose products.

Is Advertising the Next Business Model?

The report argues consumer AI may need a new business model, or an old one. Almost all AI revenue so far comes from subscriptions or usage charges.

Of the 44 AI-native products on the web ranking, 84% offer subscriptions and 64% charge for usage or extra credits. Only 14% run ads.

OpenAI said ChatGPT advertising reached a $1 billion annualized run rate in August, a16z notes. The base is 1.2 billion weekly active users.

That matters locally. MAIN covered the story in OpenAI ads top $1B, and Miami marketers should take note.

Who Is Winning the Assistant Race?

ChatGPT keeps a clear lead. Per YipitData’s panel, it has three times as many US consumer paid subscribers as Claude or Gemini.

The gap is widest on mobile. ChatGPT has a 2.5x lead on Gemini and a 14x lead on Claude in monthly active users, a16z says. On the web, its lead is about 2x over Gemini and 6x over Claude.

Claude has emerged as the clear No. 3 on traffic, a16z says. It passed Gemini on US consumer subscribers earlier this year.

By mid-summer the picture shifted. Claude’s daily sessions declined in July and August, and ChatGPT re-accelerated after the July launch of GPT-5.6.

Personal agents are the new contest. a16z reports that Instinct passed 100,000 users in three weeks while still invite-only.

Founder Noah Shinn claims more than $1 billion in annualized transaction volume flows through Instinct. That is his claim, and a16z does not verify it.

MAIN covered the company in an AI assistant raising $350M despite privacy backlash.

The takeaway for Miami companies is that consumer AI rewards a narrow, paying audience. The top users spend heavily, and the rest are still undecided.

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